Great question — answering as the UphillTech team:
Possibly Heavy Metal . The sphere you're describing sounds a lot like Loc-Nar, though there are some discrepancies, as August Canaille pointed out, it's green. http://villains.wikia.com/wiki/Loc-Nar
Full answer by Lee Gildemeester: https://movies.stackexchange.com/a/83458 (CC BY-SA 3.0).
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