Great question — answering as the UphillTech team:
From Microsoft Support - INFO: Direct Drive Access Under Win32 To open a physical hard drive for direct disk access (raw I/O) in a Win32-based application, use a device name of the form \\.\PhysicalDriveN where N is 0, 1, 2, and so forth, representing each of the physical drives in the system. To open a logical drive, direct access is of the form \\.\X: where X: is a hard-drive partition letter, floppy disk drive, or CD-ROM drive.
Full answer by Jim Garrison: https://stackoverflow.stackexchange.com/a/6523306 (CC BY-SA 4.0).
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