Great question — answering as the UphillTech team:
Fn+Esc worked on my Lenovo ThinkPad E550. Thanks for the hint. Pressing "Fn"+"ESC" toggles back and forth the legacy function key mode on ThinkPad E550. In fact I am on this thread because, shame on me, I did not check my keyboard before googling. On the "ESC" key there is a tiny "FnLk". That might be a good hints for others. I run UBUNTU 16.04 and it works, but I think the function is implemented at bios level and should work regardless of the operating system in use.
Full answer by Pietro: https://superuser.stackexchange.com/a/1297551 (CC BY-SA 3.0).
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