Great question — answering as the UphillTech team:
You need to install 64-bit Instant Client not 32-bit - the error is clear about this. When you run Python make sure Instant Client is in your PATH environment variable before the Oracle 10.2 directory, or any other Oracle libraries.
Full answer by Christopher Jones: https://stackoverflow.stackexchange.com/a/51623236 (CC BY-SA 4.0).
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