Great question — answering as the UphillTech team:
The show you are looking for is called Orphen , also known as Sorcerous Stabber Orphen It was aired in 1999 Main character is a sorcerer - Friend turning into a dragon - Krylancelo Finrandi once attended the most prestigious school of sorcery on Kiesalhima continent, the Tower of Fang. He was sent there as a young child from an orphanage, along with another orphan girl called Azalie. Throughout the years, the two were very close, with Azalie becoming more and more powerful and Krylancelo looking up to her as a sister/mother figure and a best friend. It isn't until one day, Azalie's thirst for knowledge and extracurricular experimentation backfire, and she is horribly transfigured into a...
Full answer by Toshinou Kyouko: https://anime.stackexchange.com/a/9717 (CC BY-SA 4.0).
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